In a Pickle: African Americans Struggles with Racism and Progress in Mount Olive, North Carolina, 1930-1955

This paper examines the experiences of African Americans living in Mount Olive, North Carolina during the 20th century. Life in Mount Olive afforded African Americans a multitude of opportunities such as economic, educational, and access to healthcare. Though African Americans\u27 situation in Mount Olive was better than Black people living in other locations throughout North Carolina, an exodus still occurred in the latter half of the 20th century. I argue African Americans stayed in Mount Olive because of the stability and economic opportunities provided to them by staying post-great migration, but that the persistence of racism and segregation made living there untenable, especially as these opportunities dissipated

Differences In Mechanics Between First And Second Drop Vertical Jump Landings

A drop jump and landing, followed by another maximal jump and landing, has been used when assessing injury risk utilizing the Landing Error Scoring System (LESS). Vertical ground reaction force (vGRF) and knee excursion are also commonly analyzed during a drop vertical jump. Previous studies have assessed initial drop vertical jump landing mechanics without assessing the second landing from the subsequent vertical jump. Additionally, analyzing landing mechanics based on subject jump height has not been examined for either landing 1 (L1) or landing (L2). The purpose of this study was to investigate whether there was a difference in LESS scores, vGRF, and knee excursion between the first and second landings of the drop vertical jump in all subjects and when divided into subgroups based on jump height.https://dune.une.edu/pt_studrrposter/1004/thumbnail.jp

NF-kappaB, AP-1, Zinc-deficiency and aging.

International audienceZinc (Zn) deficiency, a frequent condition in human population especially in aged persons, induces oxidative stress and subsequently activates/inhibits oxidant-sensitive transcription factors that can affect cell function, proliferation and survival leading to disease. Zn deficiency-triggered oxidative stress could affect cell signalling, including transcription factors containing Zn finger motifs and other oxidant-sensitive transcription factors such as nuclear factor kappa B (NF-kappaB) and activator protein-1 (AP-1). AP-1 can be activated in Zn deficiency that can occur secondary to an increase in cellular H(2)O(2), followed by activation of MAPKs p38 and JNK. Similarly, the cytosolic steps of the NF-kappaB cascade are activated by oxidants in Zn deficiency. However, an impaired nuclear transport of the active transcription factor leads to a low expression of NF-kappaB-dependent genes that could be involved in multiple steps of Zn deficiency associated pathology. We present here evidence that, following experimental depletion of Zn, both NF-kappaB and AP-1 signallings are altered in primary T cells isolated from young and elderly healthy individuals under CD3/CD28 costimulation. A supplementation of Zn restored both NF-kappaB and AP-1 activation in CD3/CD28 costimulated T cells from young, but not from elderly, healthy individuals, indicating that the Zn deficiency is only one component of a more complex mechanism involved in immunosenescence. In this review we summarize our present knowledge on NF-kappaB and AP-1 activation and underline the role of Zn in this process, especially in the context of Zn deficiency observed in aged persons leading to immunosenescence